Factor VIIa and antithrombin III activity during severe sepsis and septic shock in neutropenic patients.

@article{Mesters1996FactorVA,
  title={Factor VIIa and antithrombin III activity during severe sepsis and septic shock in neutropenic patients.},
  author={Rolf M. Mesters and Pier Mannuccio Mannucci and Raffaella Coppola and Tracy Keller and Hanfried Ostermann and Joachim Kienast},
  journal={Blood},
  year={1996},
  volume={88 3},
  pages={881-6}
}
Septic shock and multiple organ failure may be associated with coagulation activation, disseminated fibrin formation, and consumption of coagulation inhibitors such as antithrombin III. We have evaluated prospectively coagulation measurements in patients with severe chemotherapy-induced neutropenia. This group of patients was chosen because of their high risk of developing severe septic complications, thus allowing serial prospective coagulation testing before and during evolving sepsis or… CONTINUE READING
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