Factor V Leiden, pregnancy complications and adverse outcomes: the Hordaland Homocysteine Study.

@article{Nurk2006FactorVL,
  title={Factor V Leiden, pregnancy complications and adverse outcomes: the Hordaland Homocysteine Study.},
  author={Eha Nurk and Grethe S Tell and Helga Refsum and Per Magne Ueland and Stein Emil Vollset},
  journal={QJM : monthly journal of the Association of Physicians},
  year={2006},
  volume={99 5},
  pages={289-98}
}
BACKGROUND The factor V Leiden (FVL) mutation is the most common cause of inherited thrombophilia in Caucasian populations, and women with this variant allele are at increased risk for pregnancy complications. AIM To examine whether the FVL allele is associated with pregnancy complications and adverse outcomes in a population-based study, and to identify potential factors that interact with the FVL genotype. DESIGN Retrospective cohort study in a geographically-defined area. METHODS… CONTINUE READING
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