Factor Nrf 2-Mediated Antioxidant Defense System in the Development of Diabetic Retinopathy

@inproceedings{Zhong2013FactorN2,
  title={Factor Nrf 2-Mediated Antioxidant Defense System in the Development of Diabetic Retinopathy},
  author={Qing Zhong and Manish Mishra and Renu A Kowluru},
  year={2013}
}
Citation: Zhong Q, Mishra M, Kowluru RA. Transcription factor Nrf2-mediated antioxidant defense system in the development of diabetic retinopathy. Invest Ophthalmol Vis Sci. 2013;54:3941–3948. DOI:10.1167/ iovs.13-11598 PURPOSE. Increase in reactive oxygen species (ROS) is one of the major retinal metabolic abnormalities associated with the development of diabetic retinopathy. NF-E2–related factor 2 (Nrf2), a redox sensitive factor, provides cellular defenses against the cytotoxic ROS. In… CONTINUE READING

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