Factor J, an inhibitor of the classical and alternative complement pathway, does not inhibit esterolysis by factor D.

Abstract

Factor J (FJ) is an inhibitor of the classical and alternative complement pathways. On the classical pathway factor J disrupts the C1 component, and on the alternative pathway, factor J disrupts the C3 convertase (C3b,Bb) by a direct interaction of FJ with the components C3b and Bb. The aim of this work was to verify whether FJ could have any effect on… (More)

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@article{GonzlezRubio1996FactorJA, title={Factor J, an inhibitor of the classical and alternative complement pathway, does not inhibit esterolysis by factor D.}, author={Carolina Gonz{\'a}lez-Rubio and Rosario Gonz{\'a}lez-M{\'u}niz and M {\'A} Jim{\'e}nez-Clavero and Gumersindo Font{\'a}n and Margarita L{\'o}pez-Trascasa}, journal={Biochimica et biophysica acta}, year={1996}, volume={1295 2}, pages={174-8} }