Facilitation of inhibition in the compound lateral eye of limulus.

  title={Facilitation of inhibition in the compound lateral eye of limulus.},
  author={N Graham and Floyd Ratliff and Haldan Keffer Hartline},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={70 3},
  • N. GrahamF. RatliffH. Hartline
  • Published 1 March 1973
  • Biology, Psychology
  • Proceedings of the National Academy of Sciences of the United States of America
In the compound eye of Limulus the inhibitory effect of a burst of impulses from one group of ommatidia on the response of a neighboring ommatidium is greater when that burst is preceded by another burst of impulses. This facilitation of inhibition decays slowly, with a time constant of several seconds. Facilitation of inhibition accumulates as the number of impulses in the first burst increases, but there is a maximum that it cannot exceed. The facilitation is localized; one group of ommatidia… 

Inhibition in the Limulus Lateral Eye

The results are consistent with the idea that a single ommatidium can be inhibited by more of its neighbors in an eye in situ than in an excised eye, and that the response to inhibition could be described by a set of piecewise-linear equations.

Inhibition in the Limulus lateral eye in situ

The results are consistent with the idea that a single ommatidium can be inhibited by more of its neighbors in an eye in situ than in an excised eye and preserve the functional integrity of the retinal pathways which mediate inhibition.

Anatomical circuitry of lateral inhibition in the eye of the horseshoe crab, Limulus polyphemus

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    Proceedings of the Royal Society of London. Series B. Biological Sciences
  • 1985
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A Quantitative Description of the Dynamics of Excitation and Inhibition in the Eye of Limulus

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The effect of calcium on acetylcholine release from motor nerve terminals

  • B. KatzR. Miledi
  • Biology
    Proceedings of the Royal Society of London. Series B. Biological Sciences
  • 1965
The method of external focal recording from the neuromuscular junction has been used and it is concluded that the action of calcium is concerned directly with the release of the transmitter, and not indirectly by facilitating propagation or increasing the amplitude of the terminal nerve spike.


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It is concluded that the ribbon synapses and associated transmitter substance in eccentric cell collaterals must be inhibitory, and that two pathways for self-inhibition may exist.

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