Facilitation of a distributed shuttle-box conditioning with posttraining intracranial self-stimulation in old rats.

@article{AldavertVera1997FacilitationOA,
  title={Facilitation of a distributed shuttle-box conditioning with posttraining intracranial self-stimulation in old rats.},
  author={Laura Aldavert-Vera and David Costa-Miserachs and E Massan{\'e}s-Rotger and Carles Soriano-Mas and Pilar Segura-Torres and Ignacio Morgado-Bernal},
  journal={Neurobiology of learning and memory},
  year={1997},
  volume={67 3},
  pages={254-8}
}
Old Wistar rats (16-17 months) were trained in a two-way active avoidance task for 5 consecutive days (10 trials/day). Immediately after each training session a lateral hypothalamic intracranial self-stimulation session (ICSS group) or a sham-treatment session (Control group) was given to the animals. Long-term retention was tested 7 days after the last acquisition session. ICSS treatment led to a significant improvement in acquisition. In the long-term retention session the level of avoidance… CONTINUE READING

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