Facilitation of a dendritic calcium conductance by 5-hydroxytryptamine in the substantia nigra

@article{Nedergaard1988FacilitationOA,
  title={Facilitation of a dendritic calcium conductance by 5-hydroxytryptamine in the substantia nigra},
  author={Signe Kj{\ae}r Nedergaard and J. Paul Bolam and Susan Adele Greenfield},
  journal={Nature},
  year={1988},
  volume={333},
  pages={174-177}
}
Within the substantia nigra, the dendrites of dopaminergic neurons that project to the striatum appear to play an active and non-classical role in the physiology of the neuron in that they release transmitter and protein1, but little is known of the factors controlling release of substances from these dendrites. In this study, we show that 5-hydroxytryptamine, which is contained in afferent fibres to the substantia nigra, is present in terminals making direct synaptic contact with dopaminergic… CONTINUE READING
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