Facilitation of Ca2+ current in excitable cells.

  title={Facilitation of Ca2+ current in excitable cells.},
  author={Annette C Dolphin},
  journal={Trends in neurosciences},
  volume={19 1},
Voltage-dependent Ca2+ channels are one of the main routes for the entry of Ca2+ into excitable cells. These channels are unique in cell-signalling terms in that they can transduce an electrical signal (membrane depolarization) via Ca2+ entry into a chemical signal, by virtue of the diverse range of intracellular Ca(2+)-dependent enzymes and processes. In a variety of cell types, currents through voltage-dependent Ca2+ channels can be increased in amplitude by a number of means. Although the… CONTINUE READING

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