Facilitating actions of an AMPA receptor potentiator upon extinction of contextually conditioned fear response in stressed mice.

Abstract

Extinction of conditioned fear response is thought to be a biological process underlying exposure therapy for anxiety disorders. We have previously reported that an AMPA receptor potentiator, 4-[2-(phenylsulfonylamino)ethylthio]-2,6-difluorophenoxyacetamide (PEPA), facilitates extinction of fear memory formed through contextual fear conditioning in mice… (More)
DOI: 10.1016/j.neulet.2010.11.038

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