Faced with inequality: chicken do not have a general dosage compensation of sex-linked genes

@article{Ellegren2007FacedWI,
  title={Faced with inequality: chicken do not have a general dosage compensation of sex-linked genes},
  author={Hans Ellegren and Lina Hultin-Rosenberg and Bj{\"o}rn Brunstr{\"o}m and Lennart Dencker and Kim Kultima and Birger Scholz},
  journal={BMC Biology},
  year={2007},
  volume={5},
  pages={40 - 40}
}
BackgroundThe contrasting dose of sex chromosomes in males and females potentially introduces a large-scale imbalance in levels of gene expression between sexes, and between sex chromosomes and autosomes. In many organisms, dosage compensation has thus evolved to equalize sex-linked gene expression in males and females. In mammals this is achieved by X chromosome inactivation and in flies and worms by up- or down-regulation of X-linked expression, respectively. While otherwise widespread in… CONTINUE READING
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