Fabry disease model: a rational approach to the management of Fabry disease.

@article{Wanner2007FabryDM,
  title={Fabry disease model: a rational approach to the management of Fabry disease.},
  author={Christoph Wanner},
  journal={Clinical therapeutics},
  year={2007},
  volume={29 Suppl A},
  pages={S2-5}
}
Fabry disease (FD) is a truly progressive, multisystemic disorder. Clinically, the disease will present with 2 different faces throughout the lifetime of a patient: peripheral neurologic involvement predominates the symptoms in the first 3 decades of life (early symptoms), whereas major clinical events in the kidneys and heart or cerebrovascular system (late complications) largely determine the morbidity and mortality after 30 years of age. Before clinical manifestations occur in any organ… CONTINUE READING

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