Fabrication of novel biomaterials through molecular self-assembly

  title={Fabrication of novel biomaterials through molecular self-assembly},
  author={Shuguang Zhang},
  journal={Nature Biotechnology},
  • Shuguang Zhang
  • Published 1 October 2003
  • Chemistry, Materials Science
  • Nature Biotechnology
Two complementary strategies can be used in the fabrication of molecular biomaterials. In the 'top-down' approach, biomaterials are generated by stripping down a complex entity into its component parts (for example, paring a virus particle down to its capsid to form a viral cage). This contrasts with the 'bottom-up' approach, in which materials are assembled molecule by molecule (and in some cases even atom by atom) to produce novel supramolecular architectures. The latter approach is likely to… 
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