Fabrication of microtextured membranes for cardiac myocyte attachment and orientation.

  title={Fabrication of microtextured membranes for cardiac myocyte attachment and orientation.},
  author={J. Charlie Deutsch and Delara Motlagh and B Russell and Tejal A. Desai},
  journal={Journal of biomedical materials research},
  volume={53 3},
To understand the role of tissue adaptation to altered physiological states, a more physiologically and dimensionally relevant in vitro model of cardiac myocyte organization has been developed. A microtextured polymeric membrane with micron range dimensions promotes myocyte adhesion through substrate/cell interlocking and, thus, provides a more suitable stretchable matrix for studying overlying cell populations. These microtextured membranes are created using photolithography and… CONTINUE READING

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