Fabrication of growth factor- and extracellular matrix-loaded, gelatin-based scaffolds and their biocompatibility with Schwann cells and dorsal root ganglia.

@article{Sazo2012FabricationOG,
  title={Fabrication of growth factor- and extracellular matrix-loaded, gelatin-based scaffolds and their biocompatibility with Schwann cells and dorsal root ganglia.},
  author={Rodolfo E G{\'a}mez Sazo and Katsumi Maenaka and Weiyong Gu and Patrick McGhee Wood and Mary Bartlett Bunge},
  journal={Biomaterials},
  year={2012},
  volume={33 33},
  pages={8529-39}
}
One of the most exciting new avenues of research to repair the injured spinal cord is to combine cells for implantation with scaffolds that protect the cells and release growth factors to improve their survival and promote host axonal regeneration. To realize this goal, we fabricated biodegradable, photocurable gelatin tubes and membranes for exploratory in vitro studies. Detailed methods are described for their fabrication with a high gelatin concentration. Gelatin membranes fabricated in the… CONTINUE READING

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