Fabrication of chondroitin sulfate-chitosan composite artificial extracellular matrix for stabilization of fibroblast growth factor.

@article{Mi2006FabricationOC,
  title={Fabrication of chondroitin sulfate-chitosan composite artificial extracellular matrix for stabilization of fibroblast growth factor.},
  author={Fwu-Long Mi and Shin-Shing Shyu and Chih-Kang Peng and Yu-Bey Wu and H. -I. Sung and Pei-Shan Wang and Chi-Chuan Huang},
  journal={Journal of biomedical materials research. Part A},
  year={2006},
  volume={76 1},
  pages={1-15}
}
The development of a novel, three-dimensional, macroporous artificial extracellular matrix (AECM) based on chondroitin sulfate (ChS)-chitosan (Chito) combination is reported. The composite AECM composed of ChS-Chito conjugated network was prepared by a homogenizing interpolyelectrolyte complex/covalent conjugation technique through co-crosslinked with N,N-(3-dimethylaminopropyl)-N'-ethyl carbodiimide (EDC) and N-hydroxysuccinimide (NHS). In contrast to EDC/NHS, two different reagents, calcium… CONTINUE READING
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