Fabrication of biodegradable polymer scaffolds to engineer trabecular bone.

  title={Fabrication of biodegradable polymer scaffolds to engineer trabecular bone.},
  author={R. Y. Thomson and Michael J. Yaszemski and John Michael Powers and Antonios G Mikos},
  journal={Journal of biomaterials science. Polymer edition},
  volume={7 1},
We present a novel method for manufacturing three-dimensional, biodegradable poly(DL-lactic-co-glycolic acid) (PLGA) foam scaffolds for use in bone regeneration. The technique involves the formation of a composite material consisting of gelatin microspheres surrounded by a PLGA matrix. The gelatin microspheres are leached out leaving an open-cell foam with a pore size and morphology defined by the gelatin microspheres. The foam porosity can be controlled by altering the volume fraction of… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 82 extracted citations

Scaffolds for epithelial tissue engineering customized in elastomeric molds.

Journal of biomedical materials research. Part B, Applied biomaterials • 2018

Similar Papers

Loading similar papers…