Fabrication of a microfluidic system for capillary electrophoresis using a two-stage embossing technique and solvent welding on poly(methyl methacrylate) with water as a sacrificial layer.

@article{Koesdjojo2008FabricationOA,
  title={Fabrication of a microfluidic system for capillary electrophoresis using a two-stage embossing technique and solvent welding on poly(methyl methacrylate) with water as a sacrificial layer.},
  author={Myra T. Koesdjojo and Yolanda H. Tennico and Vincent T Remcho},
  journal={Analytical chemistry},
  year={2008},
  volume={80 7},
  pages={2311-8}
}
Methods for fabricating poly(methyl methacrylate) microchips using a novel two-stage embossing technique and solvent welding to form microchannels in microfluidic devices are presented. The hot embossing method involves a two-stage process to create the final microchip design. In its simplest form, a mold made of aluminum is fabricated using CNC machining to create the desired microchannel design. In this work, two polymer substrates with different glass transition temperatures (Tg… CONTINUE READING