Fabrication and evaluation of captopril modified-release oral formulation.

@article{Gohel2009FabricationAE,
  title={Fabrication and evaluation of captopril modified-release oral formulation.},
  author={Mukesh C. Gohel and Stavan Arunkumar Nagori},
  journal={Pharmaceutical development and technology},
  year={2009},
  volume={14 6},
  pages={679-86}
}
The present research was directed towards fabrication of modified-release captopril oral formulation. A 3(2) full factorial design was employed for optimization using captopril to Compritol ATO 888 ratio (X1) and extragranular fraction of ethyl cellulose (X2) as independent variables. The percentage drug released in 1 h (Y1) and the time required to release 80% of the drug (Y2) were selected as dependent variables. Eutectic blend of camphor and menthol was used as a solvent to facilitate the… CONTINUE READING

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Showing 1-10 of 53 references

Prediction of compressive properties of closed-cell aluminum foam using artificial neural network

  • R Raj, B. Daniel
  • Computational Mat Sci
  • 2008

Formulation and optimization of directly compressible isoniazid modified release matrix tablet

  • M Gohel, R Parikh, M Padshala, K Sarvaiya, D. Jena
  • Indian J Pharm Sci
  • 2007

Sustained release preparation containing captopril and hydrochlorothiazide and preparation process thereof

  • L. Hongshu
  • Patent No.,
  • 2007

A sustained release captopril formulation having a supermolecular intercalation structure and the preparation process thereof

  • D Xue, Z Hui, X. Xiangyu
  • Patent No.,
  • 2005

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