Fabrication and characterization of tretinoin-loaded nanofiber for topical skin delivery

  title={Fabrication and characterization of tretinoin-loaded nanofiber for topical skin delivery},
  author={Saba Khoshbakht and Farzin Asghari-Sana and Anahita Fathi-Azarbayjani and Y. Sharifi},
  journal={Biomaterials Research},
  • Saba Khoshbakht, Farzin Asghari-Sana, +1 author Y. Sharifi
  • Published 2020
  • Medicine, Materials Science
  • Biomaterials Research
  • Background Tretinoin or all-trans retinoic acid is used in the treatment of acne vulgaris and photo-aging. This work aims to develop tretinoin-loaded nanofibers as a potential anti-acne patch and to investigate its physicochemical characteristics. Method Nanofibers were produced via electrospinning method and surface topography was evaluated by Field Emission Scanning Electron Microscopy (FESEM). The functional groups of polymer and the drug molecule and the possible interactions were studied… CONTINUE READING
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