Fabrication and characterization of an inorganic gold and silica nanoparticle mediated drug delivery system for nitric oxide.

@article{Das2010FabricationAC,
  title={Fabrication and characterization of an inorganic gold and silica nanoparticle mediated drug delivery system for nitric oxide.},
  author={Amitava Das and Priyabrata Mukherjee and Sumit K Singla and Praveen Guturu and Megan Frost and Debabrata Mukhopadhyay and Vijay H Shah and Chitta Ranjan Patra},
  journal={Nanotechnology},
  year={2010},
  volume={21 30},
  pages={305102}
}
Nitric oxide (NO) plays an important role in inhibiting the development of hepatic fibrosis and its ensuing complication of portal hypertension by inhibiting human hepatic stellate cell (HSC) activation. Here we have developed a gold nanoparticle and silica nanoparticle mediated drug delivery system containing NO donors, which could be used for potential therapeutic application in chronic liver disease. The gold nanoconjugates were characterized using several physico-chemical techniques such as… CONTINUE READING
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