Fabrication and characterisation of self-applicating heparin sodium microneedle patches

  title={Fabrication and characterisation of self-applicating heparin sodium microneedle patches},
  author={Muhammad Sohail Arshad and Saman Zafar and Aleema Tehreem Zahra and MohammedH. Zaman and Ambreen Akhtar and Israfil Kucuk and Muhammad Farhan and Ming-Wei Chang and Zeeshan Ahmad},
  journal={Journal of Drug Targeting},
  pages={60 - 68}
Abstract The aim of this study was to develop heparin sodium loaded microneedle patches using different compositions of polyvinyl alcohol polymer and sorbitol. A vacuum micromolding technique was used to fabricate microneedle patches while heparin sodium was loaded into needle tips. Physical features of patches were evaluated by measuring thickness, width, folding endurance and swelling percentage. Patches were also characterised by optical microscopy and scanning electron microscopy to… Expand
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