Fab fragment glycosylated IgG may play a central role in placental immune evasion.

@article{Gu2015FabFG,
  title={Fab fragment glycosylated IgG may play a central role in placental immune evasion.},
  author={Jiang Gu and Yu Lei and Yuanping Huang and Yingying Zhao and Jing Li and Tao Huang and Junjun Zhang and Juping Wang and Xiaodong Deng and Zhengshan Chen and Christine Korteweg and Ruishu Deng and Meiling Yan and Qian Xu and Shengnan Dong and Monghong Cai and Lili Luo and Guowei Huang and Yun Wang and Qian Li and Changmei Lin and Meng Su and Chunzhang Yang and Zhengping Zhuang},
  journal={Human reproduction},
  year={2015},
  volume={30 2},
  pages={
          380-91
        }
}
STUDY QUESTION How does the placenta protect the fetus from immune rejection by the mother? SUMMARY ANSWER The placenta can produce IgG that is glycosylated at one of its Fab arms (asymmetric IgG; aIgG) which can interact with other antibodies and certain leukocytes to affect local immune reactions at the junction between the two genetically distinct entities. WHAT IS KNOWN ALREADY The placenta can protect the semi-allogenic fetus from immune rejection by the immune potent mother. aIgG in… CONTINUE READING
1
Twitter Mention

References

Publications referenced by this paper.
SHOWING 1-10 OF 53 REFERENCES

Stain–Decolorize–Stain (SDS): a new technique for multiple staining

  • Histochemistry and Cell Biology
  • 2013
VIEW 3 EXCERPTS
HIGHLY INFLUENTIAL

Similar Papers

Loading similar papers…