FZD6 expression is negatively regulated by miR-199a-5p in human colorectal cancer

@inproceedings{Kim2015FZD6EI,
  title={FZD6 expression is negatively regulated by miR-199a-5p in human
colorectal cancer},
  author={B Kim and Hye-In Yoo and Injung Kim and Jongkeun Park and Sungjoo Kim Yoon},
  booktitle={BMB reports},
  year={2015}
}
Colorectal cancer (CRC), the third most common cancer worldwide, also has the highest rate of cancer-related morbidity and mortality. WNT signaling is initiated by binding of WNT to various receptors, including frizzleds (FZDs), and plays a critical role in CRC and other tumor development by regulating proliferation, differentiation, migration, apoptosis, and polarity. Among the members of the FZD family, FZD6 is broadly expressed in various tissues, and its overexpression has been reported in… CONTINUE READING