FXYD6 is a novel regulator of Na,K-ATPase expressed in the inner ear.

@article{Delprat2007FXYD6IA,
  title={FXYD6 is a novel regulator of Na,K-ATPase expressed in the inner ear.},
  author={Benjamin Delprat and Dani{\`e}le Schaer and Sophie Roy and Jue Wang and Jean-Luc Puel and Kaethi Geering},
  journal={The Journal of biological chemistry},
  year={2007},
  volume={282 10},
  pages={7450-6}
}
The exquisite sensitivity of the cochlea, which mediates the transduction of sound waves into nerve impulses, depends on the endolymph ionic composition and the endocochlear potential. A key protein in the maintenance of the electrochemical composition of the endolymph is the Na,K-ATPase. In this study, we have looked for the presence in the rat inner ear of members of the FXYD protein family, recently identified as tissue-specific modulators of Na,K-ATPase. Only FXYD6 is detected at the… CONTINUE READING

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