FUS-CREB3L2/L1-positive sarcomas show a specific gene expression profile with upregulation of CD24 and FOXL1.

@article{Mller2011FUSCREB3L2L1positiveSS,
  title={FUS-CREB3L2/L1-positive sarcomas show a specific gene expression profile with upregulation of CD24 and FOXL1.},
  author={Emely M{\"o}ller and Jason L Hornick and Linda Magnusson and Srinivas Veerla and Henryk A. Domanski and Fredrik Mertens},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={2011},
  volume={17 9},
  pages={2646-56}
}
PURPOSE Low-grade fibromyxoid sarcoma (LGFMS) is typically characterized by the specific translocation t(7;16)(q33;p11) and the corresponding fusion gene FUS-CREB3L2. The present study aimed to extract LGFMS-specific, and putatively FUS-CREB3L2-dependent, gene expression patterns to learn more about the pathogenesis of this tumor. EXPERIMENTAL DESIGN We carried out single nucleotide polymorphism (SNP) and global gene expression array analyses, and/or immunohistochemical (IHC) analyses on 24… CONTINUE READING
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Characterization of the native CREB3L2 transcription factor and the FUS/CREB3L2 chimera. Genes Chromosomes Cancer 2007;46:181–91

  • I Panagopoulos, E M€ oller, A Dahl en, M Isaksson, N Mandahl, A VlamisGardikas
  • 2007
Highly Influential
7 Excerpts

Low grade fibromyxoid sarcoma. In:Fletcher CDM, Unni KK, Mertens F, editors. World Health Organization Classification of Tumors. Pathology and Genetics of Tumors of Soft Tissue and Bone

  • A Folpe, E Van Den Berg, WM. Molenaar
  • 2002
Highly Influential
4 Excerpts

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