FTO: the first gene contributing to common forms of human obesity

@article{Loos2008FTOTF,
  title={FTO: the first gene contributing to common forms of human obesity},
  author={R. Loos and C. Bouchard},
  journal={Obesity Reviews},
  year={2008},
  volume={9}
}
Genome‐wide association, the latest gene‐finding strategy, has led to the first major success in the field of obesity genetics with the discovery of FTO (fat mass and obesity associated gene) as an obesity–susceptibility gene. A cluster of variants in the first intron of FTO showed a strong and highly significant association with obesity‐related traits in three independent genome‐wide association studies, a finding that has been replicated in several other studies including adults and children… Expand
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References

SHOWING 1-10 OF 26 REFERENCES
Regulation of Fto/Ftm gene expression in mice and humans.
Variation in FTO contributes to childhood obesity and severe adult obesity
The Human Obesity Gene Map: The 2005 Update
Variants in the FTO gene are associated with common obesity in the Belgian population.
...
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2
3
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