FTO, Type 2 Diabetes, and Weight Gain Throughout Adult Life

@article{Hertel2011FTOT2,
  title={FTO, Type 2 Diabetes, and Weight Gain Throughout Adult Life},
  author={J. Hertel and S. Johansson and E. Sonestedt and A. Jonsson and R. T. Lie and Carl G. P. Platou and P. Nilsson and G. Rukh and K. Midthjell and K. Hveem and O. Melander and L. Groop and V. Lyssenko and A. Molven and M. Orho-Melander and P. Nj{\o}lstad},
  journal={Diabetes},
  year={2011},
  volume={60},
  pages={1637 - 1644}
}
OBJECTIVE FTO is the most important polygene identified for obesity. We aimed to investigate whether a variant in FTO affects type 2 diabetes risk entirely through its effect on BMI and how FTO influences BMI across adult life span. RESEARCH DESIGN AND METHODS Through regression models, we assessed the relationship between the FTO single nucleotide polymorphisms rs9939609, type 2 diabetes, and BMI across life span in subjects from the Norwegian population-based HUNT study using cross-sectional… Expand
Association of FTO gene variants with body composition in UK twins
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