FTIR spectral signatures of mouse antral oocytes: molecular markers of oocyte maturation and developmental competence.

@article{Ami2011FTIRSS,
  title={FTIR spectral signatures of mouse antral oocytes: molecular markers of oocyte maturation and developmental competence.},
  author={Diletta Ami and Paolo Mereghetti and Antonino Natalello and Silvia Maria Doglia and Mario Zanoni and Carlo Alberto Redi and Manuela Monti},
  journal={Biochimica et biophysica acta},
  year={2011},
  volume={1813 6},
  pages={1220-9}
}
Mammalian antral oocytes with a Hoescht-positive DNA ring around the nucleolus (SN) are able to resume meiosis and to fully support the embryonic development, while oocytes with a non-surrounded nucleolus (NSN) cannot. Here, we applied FTIR microspectroscopy to characterize single SN and NSN mouse oocytes in order to try to elucidate some aspects of the mechanisms behind the different chromatin organization that impairs the full development of NSN oocyte-derived embryos. To this aim, oocytes… CONTINUE READING

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