FTH1 Pseudogenes in Cancer and Cell Metabolism

  title={FTH1 Pseudogenes in Cancer and Cell Metabolism},
  author={M. Di Sanzo and B. Quaresima and F. Biamonte and C. Palmieri and M. C. Faniello},
  • M. Di Sanzo, B. Quaresima, +2 authors M. C. Faniello
  • Published 2020
  • Biology, Medicine
  • Cells
  • Ferritin, the principal intracellular iron-storage protein localized in the cytoplasm, nucleus, and mitochondria, plays a major role in iron metabolism. The encoding ferritin genes are members of a multigene family that includes some pseudogenes. Even though pseudogenes have been initially considered as relics of ancient genes or junk DNA devoid of function, their role in controlling gene expression in normal and transformed cells has recently been re-evaluated. Numerous studies have revealed… CONTINUE READING

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