FTH1 Pseudogenes in Cancer and Cell Metabolism

@article{Sanzo2020FTH1PI,
  title={FTH1 Pseudogenes in Cancer and Cell Metabolism},
  author={M. Di Sanzo and B. Quaresima and F. Biamonte and C. Palmieri and M. C. Faniello},
  journal={Cells},
  year={2020},
  volume={9}
}
  • M. Di Sanzo, B. Quaresima, +2 authors M. C. Faniello
  • Published 2020
  • Biology, Medicine
  • Cells
  • Ferritin, the principal intracellular iron-storage protein localized in the cytoplasm, nucleus, and mitochondria, plays a major role in iron metabolism. The encoding ferritin genes are members of a multigene family that includes some pseudogenes. Even though pseudogenes have been initially considered as relics of ancient genes or junk DNA devoid of function, their role in controlling gene expression in normal and transformed cells has recently been re-evaluated. Numerous studies have revealed… CONTINUE READING

    Figures and Tables from this paper

    References

    SHOWING 1-10 OF 129 REFERENCES
    FTH1P3, a Novel H-Ferritin Pseudogene Transcriptionally Active, Is Ubiquitously Expressed and Regulated during Cell Differentiation
    • 10
    • PDF
    H ferritin gene silencing in a human metastatic melanoma cell line: a proteomic analysis.
    • 17
    • PDF
    A FTH1 gene:pseudogene:microRNA network regulates tumorigenesis in prostate cancer
    • 33
    • Highly Influential
    • PDF
    A Human Mitochondrial Ferritin Encoded by an Intronless Gene*
    • 329
    • Highly Influential
    • PDF
    H ferritin silencing induces protein misfolding in K562 cells: A Raman analysis.
    • 17
    • PDF
    Ferritin heavy subunit enhances apoptosis of non-small cell lung cancer cells through modulation of miR-125b/p53 axis
    • 16
    • PDF
    The significance of ferritin in cancer: anti-oxidation, inflammation and tumorigenesis.
    • 126
    Mitochondrial ferritin, a new target for inhibiting neuronal tumor cell proliferation
    • 18
    • PDF
    Ferritin, iron homeostasis, and oxidative damage.
    • 437