Corpus ID: 2049649

FROM ETHNOPHARMACOLOGY TO CLINICAL STUDY OF ORTHOSIPHON STAMINEUS BENTH.

@inproceedings{Adnyana2013FROMET,
  title={FROM ETHNOPHARMACOLOGY TO CLINICAL STUDY OF ORTHOSIPHON STAMINEUS BENTH.},
  author={I Ketut Adnyana and Finna Setiawan and Muhamad Insanu},
  year={2013}
}
Extensive research has been carried out on Orthosiphon stamineus Benth. (lamiaceae) since the 1930s. This plant is used in several countries (especially in Indonesia, Malaysia, Thailand, Vietnam and Myanmar) as traditional medicine. From its ethnobotanical uses the plant is known for several activities. Because of those reasons, O. stamineus is potential to be developed as a new source of drugs. This report comprehensively reviews ethnopharmacological, isolated chemical compounds… Expand
Thin Layer Chromatography Fingerprinting and Clustering of Orthosiphon stamineus Benth. from Different Origins
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TLDR
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INVITRO STUDY ON ANTIDIABETIC, ANTIOXIDANT, ANTI-INFLAMMATORY, ANTI-OBESITY PROPERTIES OF POLYPHENOL RICH FRACTION FROM THE LEAVES OF ORTHOSPHON STAMINEUS
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HPLC fingerprinting coupled with linear discriminant analysis for the detection of adulteration in Orthosiphon aristatus
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References

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Phytochemical and pharmacological studies on Orthosiphon stamineus Benth. (Lamiaceae) hydroalcoholic extracts.
The main components of Orthosiphon stamineus Benth. leaves and extracts are the pharmacologically active polyphenols: the polymethoxylated flavonoids and the caffeic acid derivatives. Two tinctures,Expand
Evaluation of nephroprotective activity of Orthosiphon stamineus Benth extract using rat model.
The work was undertaken to carry out the preliminary phytochemical studies and Nephroprotective activity of orthosiphon stamineus family Laminaceae (Labiateae). These studies revealed the presence ofExpand
Constituents of the Vietnamese medicinal plant Orthosiphon stamineus.
TLDR
All the isolated compounds were tested for their cytotoxicity towards highly liver metastatic murine colon 26-L5 carcinoma cells, and the new diterpenes, except for 4, and flavonoids showed cytot toxicity with an ED50 value between 10 and 90 microg/ml. Expand
Indonesian medicinal plants. XXIII. Chemical structures of two new migrated pimarane-type diterpenes, neoorthosiphols A and B, and suppressive effects on rat thoracic aorta of chemical constituents isolated from the leaves of Orthosiphon aristatus (Lamiaceae).
Two novel migrated pimarane-type diterpenes named neoorthosiphols A (1) and B (2) were isolated from the water decoction of the leaves of Orthosiphon aristatus (Lamiaceae), which has been prescribedExpand
Adenosine A1 receptor binding activity of methoxy flavonoids from Orthosiphon stamineus.
TLDR
The results of this study provide a scientific foundation for the traditional use of Orthosiphon stamineus in kidney stone treatment, as the affinity of the active compounds isolated from it as adenosine A (1) receptor ligands allows them to be associated with diuretic activity, which is one possible treatment for renal lithiasis. Expand
Antioxidant and hepatoprotective effects of Orthosiphon stamineus Benth. standardized extract.
TLDR
The results of the present study indicated that the hepatoprotective effect of Orthosiphon stamineus might be ascribable to its antioxidant and free radical scavenging property. Expand
[Antihypertensive substance in the leaves of kumis kucing (Orthosiphon aristatus) in Java Island].
TLDR
It was found that a major constituent in the water decoction of leaves, methylripariochromene A (5), exhibited a continuous decrease in systolic blood pressure after subcutaneous administration in conscious stroke-prone spontaneously hypertensive rats (SHRSP). Expand
Antihyperglycemic Effect of Orthosiphon Stamineus Benth Leaves Extract and Its Bioassay-Guided Fractions
TLDR
It appears that Cƒ2-B functions similarly to metformin, which has no hypoglycemic effect but demonstrates an antihyperglycemic effect only in normogycemic models and may have no direct stimulatory effects on insulin secretion or on blood glucose levels in diabetic animal models. Expand
Chemical composition analysis and antioxidant activity evaluation of essential oil from Orthosiphon thymiflorus (Roth) Sleesen
Abstract Objective Orthosiphon thymiflorus (Roth) Sleesen (O. thymiflorus) is an aromatic plant widely distributed in the Western Ghats of South India. The present study investigates the chemicalExpand
Hepatoprotective Activity of "Orthosiphon stamineus" on Liver Damage Caused by Paracetamol in Rats
The objective of this study was to investigate the hepatoprotective activity of Methanol extract of leaves of Orthosiphon stamineus against paracetamol induced hepatotoxicity. The material was driedExpand
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