FRG1P is localised in the nucleolus, Cajal bodies, and speckles.

@article{Koningsbruggen2004FRG1PIL,
  title={FRG1P is localised in the nucleolus, Cajal bodies, and speckles.},
  author={Silvana van Koningsbruggen and Roeland W. Dirks and A. Mieke Mommaas and Jos J. M. Onderwater and Giancarlo Deidda and George W. Padberg and Rune R. Frants and Silv{\'e}re M. van der Maarel},
  journal={Journal of medical genetics},
  year={2004},
  volume={41 4},
  pages={e46}
}
T he highly conserved facioscapulohumeral muscular dystrophy (FSHD) region gene 1 (FRG1) was initially cloned as candidate gene of unknown function for FSHD. To explore the biological function of the FRG1 protein (FRG1P), we studied its cellular localisation in untransfected and FRG1 transfected cell lines. In interphase cells, FRG1P is localised in the dense structures of the nucleolus, in Cajal bodies, and in 60–80% of cells in nuclear speckles. A time course study revealed that FRG1P… CONTINUE READING
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