FRET quenching of photosensitizer singlet oxygen generation.

  title={FRET quenching of photosensitizer singlet oxygen generation.},
  author={J. Lovell and Juan Chen and M. Jarvi and W. Cao and A. D. Allen and Yuanqin Liu and T. Tidwell and B. Wilson and G. Zheng},
  journal={The journal of physical chemistry. B},
  volume={113 10},
The development of activatable photodynamic therapy (PDT) has demonstrated a utility for effective photosensitizer quenchers. However, little is known quantitatively about Forster resonance energy transfer (FRET) quenching of photosensitizers, even though these quenchers are versatile and readily available. To characterize FRET deactivation of singlet oxygen generation, we attached various quenchers to the photosensitizer pyropheophorbide-alpha (Pyro) using a lysine linker. The linker did not… Expand
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