FREE AMINO ACIDS IN DEVELOPING RAT RETINA

@article{Macaione1974FREEAA,
  title={FREE AMINO ACIDS IN DEVELOPING RAT RETINA},
  author={Salvatore Macaione and Piero Ruggeri and Filippo De Luca and Gregory C. Tucci},
  journal={Journal of Neurochemistry},
  year={1974},
  volume={22}
}
—During postnatal growth the free amino acids pattern of rat retina differs at various developmental stages. The adult level for individual amino acids is reached on the 30th day of maturation. During differentiation the taurine, glutamic acid, GABA, glutamine, aspartic acid, glycine arginine, methionine and histidine levels increase while proline. alanine, ornithine and tyrosine decrease. 
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Results show that experimental diabetes produces a generalized fall in the content of free amino acids in both retina and retinal pigment epithelium, which might suggest that diabetes causes alterations of specific amino acid transport systems and/or alterations of some cell populations.
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Branched chain amino acid metabolism in the retina of diabetic rats
TLDR
The results suggest that the major role for the branched chain amino acids in the rat retina is in protein synthesis which is not affected by short-term diabetes.
Role of Taurine in Brain Development and Vision
TLDR
It is apparent that taurine has fundamental, but undetermined function(s) on the brain and eye, but whether it is multifunctional and encompasses some or all of these functions, remains to be determined.
Taurine and other free amino acids in the retina, vitreous, lens, irisciliary body, and cornea of the rat eye
TLDR
Taurine was the most abundant amino acid in all five tissue studied, and its high concentration in non-neural tissues, especially the lens, suggests that it must have other functions as well as neurotransmitter ones in the rat eye.
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