FR209602 and Related Compounds, Novel Antifungal Lipopeptides from Coleophoma crateriformis No. 738
@article{Kanasaki2006FR209602AR, title={FR209602 and Related Compounds, Novel Antifungal Lipopeptides from Coleophoma crateriformis No. 738}, author={Ryuichi Kanasaki and Fumie Abe and Shigetada Furukawa and Koji Yoshikawa and Akihiko Fujie and Motohiro Hino and Seiji Hashimoto and Yasuhiro Hori}, journal={The Journal of Antibiotics}, year={2006}, volume={59}, pages={145-148} }
The biological activities of the novel echinocandin-like lipopeptides, FR209602, FR209603 and FR209604, were evaluated. These compounds showed antifungal activity against Candida albicans and Aspergillus fumigatus attributed to inhibition of 1,3-β-glucan synthesis. The minimum effective concentrations of these compounds against C. albicans and A. fumigatus ranged from 0.02 to 0.04 µg/ml by microbroth dilution assay, and the IC50 values on C. albicans 1,3-β-glucan synthase were 0.49, 0.64 and 0…
13 Citations
FR209602 and Related Compounds, Novel Antifungal Lipopeptides from Coleophoma crateriformis No. 738
- BiologyThe Journal of Antibiotics
- 2006
Novel antifungal lipopeptides, FR209602, FR209603 and FR209604, were isolated from the fermentation broth of a fungal strain No. 738 which was identified as Coleophoma crateriformis from…
FR227673 and FR190293, Novel Antifungal Lipopeptides from Chalara sp. No. 22210 and Tolypocladium parasiticum No. 16616
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Novel antifungal lipopeptides, FR227673 and FR190293, were isolated from the fermentation broths of fungal strains Chalara sp. No. 22210 and Tolypocladium parasiticum No. 16616, respectively. These…
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