FR209602 and Related Compounds, Novel Antifungal Lipopeptides from Coleophoma crateriformis No. 738

@article{Kanasaki2006FR209602AR,
  title={FR209602 and Related Compounds, Novel Antifungal Lipopeptides from Coleophoma crateriformis No. 738},
  author={Ryuichi Kanasaki and Fumie Abe and Shigetada Furukawa and Koji Yoshikawa and Akihiko Fujie and Motohiro Hino and Seiji Hashimoto and Yasuhiro Hori},
  journal={The Journal of Antibiotics},
  year={2006},
  volume={59},
  pages={145-148}
}
The biological activities of the novel echinocandin-like lipopeptides, FR209602, FR209603 and FR209604, were evaluated. These compounds showed antifungal activity against Candida albicans and Aspergillus fumigatus attributed to inhibition of 1,3-β-glucan synthesis. The minimum effective concentrations of these compounds against C. albicans and A. fumigatus ranged from 0.02 to 0.04 µg/ml by microbroth dilution assay, and the IC50 values on C. albicans 1,3-β-glucan synthase were 0.49, 0.64 and 0… 
FR209602 and Related Compounds, Novel Antifungal Lipopeptides from Coleophoma crateriformis No. 738
Novel antifungal lipopeptides, FR209602, FR209603 and FR209604, were isolated from the fermentation broth of a fungal strain No. 738 which was identified as Coleophoma crateriformis from
FR227673 and FR190293, Novel Antifungal Lipopeptides from Chalara sp. No. 22210 and Tolypocladium parasiticum No. 16616
Novel antifungal lipopeptides, FR227673 and FR190293, were isolated from the fermentation broths of fungal strains Chalara sp. No. 22210 and Tolypocladium parasiticum No. 16616, respectively. These
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