FOXO3a Gene Polymorphism Associated with Asthma in Indian Population

  title={FOXO3a Gene Polymorphism Associated with Asthma in Indian Population},
  author={Shravani Barkund and Tejas Shah and Nikhil Ambatkar and Maithili S. Gadgil and Kalpana S. Joshi},
  booktitle={Molecular biology international},
Asthma is a chronic inflammatory disorder delineated by a heightened immunological response due to environmental or genetic factors. Single nucleotide polymorphism studies have shown that FOXO3a plays a pivotal role in maintaining immunoregulation. Polymorphism in FOXO3a has been linked to inflammatory diseases such as chronic obstructive pulmonary disease (COPD), Rheumatoid Arthritis, and Crohn's disease suggesting that FOXO3a may be associated with asthma. Airway inflammation in asthma is… CONTINUE READING
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