FOXO1, TGF-β Regulation and Wound Healing

  title={FOXO1, TGF-β Regulation and Wound Healing},
  author={Alhassan Hameedaldeen and Jian Liu and Angelika Batres and Gabrielle S. Graves and Dana T Graves},
  booktitle={International journal of molecular sciences},
Re-epithelialization is a complex process that involves migration and proliferation of keratinocytes, in addition to the production of cytokines and growth factors that affect other cells. The induction of transcription factors during these processes is crucial for successful wound healing. The transcription factor forkhead boxO-1 (FOXO1) has recently been found to be an important regulator of wound healing. In particular, FOXO1 has significant effects through regulation of transforming growth… CONTINUE READING