FOXO-dependent regulation of innate immune homeostasis

@article{Becker2010FOXOdependentRO,
  title={FOXO-dependent regulation of innate immune homeostasis},
  author={Thomas Becker and Gerrit Loch and Marc Beyer and Ingo Zinke and A C Aschenbrenner and Pilar Carrera and Therese Inhester and Joachim L. Schultze and Michael Hoch},
  journal={Nature},
  year={2010},
  volume={463},
  pages={369-373}
}
The innate immune system represents an ancient host defence mechanism that protects against invading microorganisms. An important class of immune effector molecules to fight pathogen infections are antimicrobial peptides (AMPs) that are produced in plants and animals. In Drosophila, the induction of AMPs in response to infection is regulated through the… CONTINUE READING