FOXO/TXNIP pathway is involved in the suppression of hepatocellular carcinoma growth by glutamate antagonist MK-801

Abstract

Accumulating evidence has suggested the importance of glutamate signaling in cancer growth, yet the signaling pathway has not been fully elucidated. N-methyl-D-aspartic acid (NMDA) receptor activates intracellular signaling pathways such as the extracellular-signal-regulated kinase (ERK) and forkhead box, class O (FOXO). Suppression of lung carcinoma growth… (More)
DOI: 10.1186/1471-2407-13-468

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Cite this paper

@inproceedings{Yamaguchi2013FOXOTXNIPPI, title={FOXO/TXNIP pathway is involved in the suppression of hepatocellular carcinoma growth by glutamate antagonist MK-801}, author={Fuminori Yamaguchi and Yuko Hirata and Hossain Akram and Kazuyo Kamitori and Youyi Dong and Li Sui and Masaaki Tokuda}, booktitle={BMC Cancer}, year={2013} }