FOXA1 expression in breast cancer--correlation with luminal subtype A and survival.

@article{Badve2007FOXA1EI,
  title={FOXA1 expression in breast cancer--correlation with luminal subtype A and survival.},
  author={Sunil S Badve and Dmitry A. Turbin and Mangesh A. Thorat and Akira Morimiya and Torsten O. Nielsen and Charles M. Perou and Sandi Dunn and David G. Huntsman and Harikrishna Nakshatri},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={2007},
  volume={13 15 Pt 1},
  pages={4415-21}
}
PURPOSE FOXA1, a forkhead family transcription factor, is essential for optimum expression of approximately 50% of estrogen receptor alpha (ERalpha):estrogen responsive genes. FOXA1 is expressed in breast cancer cells. It segregates with genes that characterize the luminal subtypes in DNA microarray analyses. The utility of FOXA1 as a possible independent prognostic factor has not been determined in breast cancers. MATERIALS AND METHODS A tissue microarray comprising tumors from 438 patients… CONTINUE READING
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