• Corpus ID: 62806138

FORMULATION AND EVALUATION OF AN HERBAL ANTI-INFLAMMATORY GEL CONTAINING TRIGONELLA FOENUM GREACUM SEED EXTRACT

@article{Jyothi2015FORMULATIONAE,
  title={FORMULATION AND EVALUATION OF AN HERBAL ANTI-INFLAMMATORY GEL CONTAINING TRIGONELLA FOENUM GREACUM SEED EXTRACT},
  author={D. Shanmukhi Jyothi and Marina Koland},
  journal={International Journal of Pharmacy and Pharmaceutical Sciences},
  year={2015},
  volume={8},
  pages={41-44}
}
  • D. Jyothi, M. Koland
  • Published 18 November 2015
  • Biology
  • International Journal of Pharmacy and Pharmaceutical Sciences
Objective: The present study was aimed to develop topical gel containing Trigonella foenum greacum (fenugreek) seed extract using carbopol-934, Hydroxypropyl methylcellulose K4M (HPMC K4M) as gelling agents and to investigate the anti-inflammatory activity of suitable gel formulation. Methods: Gels were prepared using carbopol-934, HPMC K4M individually as well as in combination as gelling agents. Prepared formulations were evaluated for various physicochemical properties. Based on in vitro… 

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References

SHOWING 1-10 OF 14 REFERENCES
FORMULATION DEVELOPMENT AND STANDARDISATION OF HERBAL GEL CONTAINING METHANOLIC EXTRACT OF BUTEA FRONDOSA
The present research has been undertaken with the aim to formulate an d evaluate the herbal gel containing Butea frondosa extract. The gel formulation was designed by using methanol extract of Butea
FORMULATION AND EVALUATION OF CLOBETASOL PROPIONATE GEL
Objective: The aim of the study was to formulate Clobetasol propionate into a gel formulation using carbopol-934, Hydroxypropyl methylcellulose K4M, sodium alginate, Carboxymethylcellulose Sodium as
Effect of cream formulation of fenugreek seed extract on some mechanical parameters of human skin.
TLDR
Both the cream base and the cream containing fenugreek extract demonstrated significant improvement in all mechanical parameters related to skin elasticity, ageing, hydration and fatigue but the effect of the extract cream was more pronounced in some cases.
Formulation and evaluation of Gel containing Fluconazole-Antifungal Agent
TLDR
Efficient delivery of drug to skin application was found to be highly beneficial in localizing the drug to desired site in the skin and reduced side effects associated with conventional treatment.
Formulation and evaluation of ciprofloxacin as a topical gel
TLDR
The overall results of this study suggest that the selected formula could be used in the preparation of ciprofloxacin gel as a topical dosage form to be used inthe treatment of some dermatological infections.
Antioxidative Activity of Extracts from Fenugreek Seeds (Trigonella foenum-graecum)
Spices and herbs possess antioxidant activity and can be applied for preservation of lipid peroxidation in biological systems. Fenugreek (Trigonella foenum-graecum) is an important spice; its dried
Antioxidant properties of germinated fenugreek seeds
TLDR
This study reveals significant antioxidant activity in germinated fenugreek seeds which may be due partly to the presence of flavonoids and polyphenols.
[Studies on flavonoids from Fenugreek (Trigonella foenumgraecum L.)].
  • M. Shang, S. Cai, W. Fan
  • Chemistry, Medicine
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
  • 1998
TLDR
Three flavonoids, tricin, naringenin andtricin-7-O-beta-D-glucopyranoside, were isolated from fenugreek as well as from the plants of Trigonella for the first time.
Mechanisms of action of topical therapies and the rationale for combination therapy.
  • D. Norris
  • Medicine, Biology
    Journal of the American Academy of Dermatology
  • 2005
...
...