FOG acts as a repressor of red blood cell development in Xenopus.

@article{Deconinck2000FOGAA,
  title={FOG acts as a repressor of red blood cell development in Xenopus.},
  author={Anne E. Deconinck and Paul Evan Mead and Sergei G. Tevosian and John D. Crispino and Samuel G. Katz and Leonard I. Zon and Stuart H Orkin},
  journal={Development},
  year={2000},
  volume={127 10},
  pages={2031-40}
}
Members of the GATA family of zinc-finger transcription factors have critical roles in a variety of cell types. GATA-1, GATA-2 and GATA-3 are required for proliferation and differentiation of several hematopoietic lineages, whereas GATA-4, GATA-5 and GATA-6 activate cardiac and endoderm gene expression programs. Two GATA cofactors have recently been identified. Friend of GATA-1 (FOG-1) interacts with GATA-1 and is expressed principally in hematopoietic lineages, whereas FOG-2 is expressed… CONTINUE READING