FOCUS: an alignment-free model to identify organisms in metagenomes using non-negative least squares

@inproceedings{Silva2014FOCUSAA,
  title={FOCUS: an alignment-free model to identify organisms in metagenomes using non-negative least squares},
  author={Genivaldo Gueiros Z. Silva and Daniel Cuevas and Bas E. Dutilh and Robert A. Edwards},
  booktitle={PeerJ},
  year={2014}
}
One of the major goals in metagenomics is to identify the organisms present in a microbial community from unannotated shotgun sequencing reads. Taxonomic profiling has valuable applications in biological and medical research, including disease diagnostics. Most currently available approaches do not scale well with increasing data volumes, which is important because both the number and lengths of the reads provided by sequencing platforms keep increasing. Here we introduce FOCUS, an agile… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 33 times over the past 90 days. VIEW TWEETS