FLICE-inhibitory protein: expression in early and late gestation human placentas.

@article{Ka2006FLICEinhibitoryPE,
  title={FLICE-inhibitory protein: expression in early and late gestation human placentas.},
  author={Hakhyun Ka and Joan S. Hunt},
  journal={Placenta},
  year={2006},
  volume={27 6-7},
  pages={626-34}
}
The apoptosis cascade that plays a central role in normal and pathological processes is strictly controlled, in part by FLIP (Fas-associated death domain-like interleukin-1beta-converting enzyme-inhibitory protein), an inhibitor of caspase-8. Here, we report the expression of long and short isoforms of FLIP mRNAs and proteins in early and late gestation human placentas, term cytotrophoblast cells and two choriocarcinoma cell lines, JEG-3 and Jar. Reverse transcriptase polymerase chain reaction… CONTINUE READING