FKBP5 risk alleles and the development of intrusive memories

  title={FKBP5 risk alleles and the development of intrusive memories},
  author={J. Cheung and Richard A. Bryant},
  journal={Neurobiology of Learning and Memory},
Intrusive memories are unwanted recollections that maintain distress and are central to numerous psychological disorders, including posttraumatic stress disorder (PTSD). Convergent evidence suggests that glucocorticoid increases enhance the strength of emotional memories. The FKBP5 polymorphism modulates glucocorticoid receptor sensitivity, and has been shown to increase risk for PTSD. Healthy high and low risk FKBP5 allele carriers (N=46) underwent a cold pressor task, and then viewed negative… CONTINUE READING