FKBP5 and attention bias for threat: associations with hippocampal function and shape.

@article{Fani2013FKBP5AA,
  title={FKBP5 and attention bias for threat: associations with hippocampal function and shape.},
  author={Negar Fani and David H. Gutman and Erin B Tone and Lynn M. Almli and Kristina B. Mercer and Jennifer Nason Davis and Ebony M. Glover and Tanja Jovanovic and Bekh Bradley and Ivo D. Dinov and Alen Zamanyan and Arthur W. Toga and Elisabeth B. Binder and Kerry J. Ressler},
  journal={JAMA psychiatry},
  year={2013},
  volume={70 4},
  pages={
          392-400
        }
}
IMPORTANCE The FKBP5 gene product regulates glucocorticoid receptor (GR) sensitivity and hypothalamic-pituitary-adrenal axis functioning and has been associated with many stress-related psychiatric disorders. The study of intermediate phenotypes, such as emotion-processing biases and their neural substrates, provides a way to clarify the mechanisms by which FKBP5 dysregulation mediates risk for psychiatric disorders. OBJECTIVE To examine whether allelic variations for a putatively functional… CONTINUE READING
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