FIV induced encephalopathy: early brain lesions in the absence of viral replication in monocyte/macrophages. A pathogenetic model.

@article{Silvotti1997FIVIE,
  title={FIV induced encephalopathy: early brain lesions in the absence of viral replication in monocyte/macrophages. A pathogenetic model.},
  author={Lucia Silvotti and Attilio Corradi and Giorgio Brandi and Aderville Cabassi and Mauro Bendinelli and Mireille Magnan and Giuseppe Piedimonte},
  journal={Veterinary immunology and immunopathology},
  year={1997},
  volume={55 4},
  pages={263-71}
}
FIV induced encephalopathy represents a model for the study of the neuropathogenesis of AIDS. It has yet to be determined whether massive viral replication is a prerequisite for the development of early brain lesions. Using a drug delivery system developed by us, we have shown that early encephalic lesions appear in FIV infected subjects even when viral… CONTINUE READING