FISH for pre-implantation genetic diagnosis.

@article{Scriven2010FISHFP,
  title={FISH for pre-implantation genetic diagnosis.},
  author={Paul N Scriven and Caroline M. Ogilvie},
  journal={Methods in molecular biology},
  year={2010},
  volume={659},
  pages={269-82}
}
Pre-implantation genetic diagnosis (PGD) is an established alternative to pre-natal diagnosis, and involves selecting pre-implantation embryos from a cohort generated by assisted reproduction technology (ART). This selection may be required because of familial monogenic disease (e.g. cystic fibrosis), or because one partner carries a chromosome rearrangement (e.g. a two-way reciprocal translocation). PGD is available for couples who have had previous affected children, and/or in the case of… CONTINUE READING

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