FISH analysis of hematological neoplasias with 1p36 rearrangements allows the definition of a cluster of 2.5 Mb included in the minimal region deleted in 1p36 deletion syndrome

@article{Lahortiga2005FISHAO,
  title={FISH analysis of hematological neoplasias with 1p36 rearrangements allows the definition of a cluster of 2.5 Mb included in the minimal region deleted in 1p36 deletion syndrome},
  author={Idoya Lahortiga and Iria V{\'a}zquez and Elena Belloni and Jos{\'e} P. Rom{\'a}n and Patrizia Gasparini and Francisco J. Novo and Isabel Zudaire and Pier Giuseppe Pelicci and Jes{\'u}s Ma Hern{\'a}ndez and Mar{\'i}a Jos{\'e} Calasanz and Mar{\'i}a Dolores Odero},
  journal={Human Genetics},
  year={2005},
  volume={116},
  pages={476-485}
}
Rearrangements in the distal region of the short arm of chromosome 1 are recurrent aberrations in a broad spectrum of human neoplasias. However, neither the location of the breakpoints (BP) on 1p36 nor the candidate genes have been fully determined. We have characterized, by fluorescence in situ hybridization (FISH), the BP in 26 patients with hematological neoplasias and 1p36 rearrangements in the G-banding karyotype. FISH allowed a better characterization of all samples analyzed. Nine cases… CONTINUE READING

References

Publications referenced by this paper.
Showing 1-10 of 54 references

Mitelman database of chromosome aberrations in cancer

  • F Mitelman, B Johansson, F Mertens
  • 2003
Highly Influential
4 Excerpts

Similar Papers

Loading similar papers…