FISH analysis comparing genome organization in the domestic horse (Equus caballus) to that of the Mongolian wild horse (E. przewalskii)

@article{Myka2003FISHAC,
  title={FISH analysis comparing genome organization in the domestic horse (Equus caballus) to that of the Mongolian wild horse (E. przewalskii)},
  author={Jennifer Leigh Myka and Teri L. Lear and Marlys L. Houck and Oliver A. Ryder and Ernest Bailey},
  journal={Cytogenetic and Genome Research},
  year={2003},
  volume={102},
  pages={222 - 225}
}
Przewalski’s wild horse (E. przewalskii, EPR) has a diploid chromosome number of 2n = 66 while the domestic horse (E. caballus, ECA) has a diploid chromosome number of 2n = 64. [...] Key Method To determine which EPR chromosomes were homologous to ECA5 and to confirm the predicted chromosome homologies based on GTG banding, we constructed a comparative gene map between ECA and EPR by FISH mapping 46 domestic horse-derived BAC clones containing genes previously mapped to ECA chromosomes. The results indicated…Expand
Comparative chromosomal studies of E. caballus (ECA) and E. przewalskii (EPR) in a female F1 hybrid.
  • E. Ahrens, G. Stranzinger
  • Biology, Medicine
    Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie
  • 2005
TLDR
The formation of a trivalent during meiosis in a male F1 hybrid and the homologies in G-banding patterns suggest that ECA 5 corresponds to two acrocentric EPR chromosomes resulting from a Robertsonian fusion or fission event.
Horse domestication and conservation genetics of Przewalski's horse inferred from sex chromosomal and autosomal sequences.
TLDR
X chromosomal and autosomal data do not place Przewalski's horses in a separate clade within phylogenetic trees for horses, suggesting a close relationship between domestic and Przine's horses and the hypothesis that very few male horses along with numerous female horses founded the various domestic horse breeds is supported.
Analysis of horse genomes provides insight into the diversification and adaptive evolution of karyotype
TLDR
The analysis results of the two representative Equus species genomes improved the knowledge of Equus chromosome rearrangement and karyotype evolution and discovered the percentages of LINE_L1 and LTR_ERV1 are significantly increased in rearrangements regions.
COMPARATIVE MAPPING: HOMOLOGY WITHIN THE ORDER PERISSODACTYLA OF FOUR GENES LOCATED ON EQUUS CABALLUS CHROMOSOME 20
TLDR
It is apparent the chromosome has gone through several morphological changes while undergoing speciation in the Equidae, yet the overall gene order is conserved.
Homologous fission event(s) implicated for chromosomal polymorphisms among five species in the genus Equus
TLDR
Evidence is reported that the polymorphism involves the same homologous chromosome segments in each species, and that these chromosome segments have homology to human chromosome 4 (HSA4) and that this polymorphism is either ancient and conserved within the genus or has occurred recently and independently within each species.
Phylogeny of Horse Chromosome 5q in the Genus Equus and Centromere Repositioning
TLDR
This analysis traced the phylogeny of horse chromosome 5, analyzing the order of BAC markers, derived from a horse genomic library, in 7 Equus species and showed that repositioned centromeres are present in E. asinus and E. burchelli, confirming that centromere repositioning is a strikingly frequent phenomenon in this genus.
Genome collinearity analysis illuminates the evolution of donkey chromosome 1 and horse chromosome 5 in perissodactyls: A comparative study
TLDR
The cytogenetic nomenclature is identified, the direction of the chromosome-length sequence of the donkey genome is corrected, and the genome-wide chromosomal rearrangements between the donkey and horse are analyzed, which supports the correctness of the existing Equus phylogeny to an extent.
A high-resolution physical map of equine homologs of HSA19 shows divergent evolution compared with other mammals
A high-resolution (1 marker/700 kb) physically ordered radiation hybrid (RH) and comparative map of 122 loci on equine homologs of human Chromosome 19 (HSA19) shows a variant evolution of these
Subchromosomal karyotype evolution in Equidae
TLDR
The results indicate that the prevailing type of fusion in Equidae is centric fusion, and subchromosomal comparative mapping results suggested that tiny centromere repositioning or pericentric inversions are quite frequent in zebras and asses.
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