FINDSITELHM: A Threading-Based Approach to Ligand Homology Modeling


Ligand virtual screening is a widely used tool to assist in new pharmaceutical discovery. In practice, virtual screening approaches have a number of limitations, and the development of new methodologies is required. Previously, we showed that remotely related proteins identified by threading often share a common binding site occupied by chemically similar… (More)
DOI: 10.1371/journal.pcbi.1000405


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